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Most cases of early-onset AD arise sporadically, but others are inherited, usually in polygenic fashion, although in a few families there is a dominant gene. B Variants resulting from elongation of the internal carotid artery (shown for the left artery): A C-shaped course, B S-shaped course, C coiling, D double coiling, E kink- ing, F double kinking References 215 References 1.

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