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The new interactions in the spHceosome which occur after the first step are: U5 interaction with exon 2; the non-canonical G-G interaction between the first and last intron nucleotides (pink line); the tertiary interaction between U2 and U6 (yellow line); cross-links between U6 and intron 2 (orange line) and between U2 and exon 2 (light blue line); and the new 2'-5' A-G bond at the lariat branch (green line).

1 326 459. Our group has synthesized acetal-terminated PEO-b-PCL through anionic ROP of g-caprolactone by acetal-PEO (Figure 13.

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